Concepedia

Involvement of endoplasmic reticulum stress-activated PERK-eIF2α-ATF4 signaling pathway in T-2 toxin-induced apoptosis of porcine renal epithelial cells

Xiangyan Liu, Ze Wang, Xianglin Wang, Xiaona Yan, Qing He, Sha Liu, Mengke Ye, Xiaowen Li, Zhihang Yuan, Jing Wu,

Toxicology and Applied Pharmacology · 2021 · 23 citations · 49 references

DOI

Concepts

References

49

BiP Binding to the ER-Stress Sensor Ire1 Tunes the Homeostatic Behavior of the Unfolded Protein Response

David Pincus, Michael Chevalier, Tomás Aragón et al. · PLoS Biology · 2010 · 437 citations · Full text

, , +14

Optimization of the Tetrazolium Dye (MTT) Colorimetric Assay for Cellular Growth and Viability

Paul W. Sylvester · Methods in molecular biology · 2011 · 435 citations

, , +11

UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor

Megan C Kopp, Natacha Larburu, Vinoth Durairaj et al. · Nature Structural & Molecular Biology · 2019 · 407 citations · Full text

, , +10

The luminal domain of the ER stress sensor protein PERK binds misfolded proteins and thereby triggers PERK oligomerization

Peng Wang, Jingzhi Li, Jiahui Tao et al. · Journal of Biological Chemistry · 2018 · 140 citations · Full text

, , +17

Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival

Franziska Walter, Jasmin Schmid, Caoimhín G. Concannon et al. · Cell Death and Differentiation · 2015 · 128 citations · Full text

, , +17