Hsp90 up-regulates PD-L1 to promote HPV-positive cervical cancer via HER2/PI3K/AKT pathway

Abstract

In this study, we demonstrated a promising tumor-suppressive effect of Hsp90 knockdown in HPV16⁺ cervical cancers, and investigated the underlying molecular pathway. Our results suggested that Hsp90 knockdown holds great therapeutic potential in treating HPV16⁺ cervical cancers.