<i>N</i>‐Iodosuccinimide‐promoted Regioselective Selenylation of 4<i>H</i>‐Pyrido‐[1,2‐<i>a</i>]‐pyrimidin‐4‐ones with Diselenides at Room Temperature

Abstract

Abstract A novel and efficient approach for the regioselective selenylation of 4 H ‐pyrido‐[1,2‐ a ]‐pyrimidin‐4‐ones with diselenides at room temperature has been developed. This procedure is catalyzed by N ‐iodosuccinimide under metal‐free conditions with a broad range of substrate scopes and affords C3 selenylation products in good to excellent yields. Furthermore, the sulfenylation with diphenyl disulfides and 4‐methylbenzenethiol in this transformation is successful.