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Discovery of 1,8-naphthalidine derivatives as potent anti-hepatic fibrosis agents via repressing PI3K/AKT/Smad and JAK2/STAT3 pathways

InflammationMedicinal ChemistryPharmaceutical ChemistryAnti-inflammatoryBiochemistryMedicineLiver PhysiologyNatural SciencesPharmacological AgentJak2/stat3 PathwaysHepatotoxicityPharmacotherapyHepatology Fibrosis1,8-Naphthalidine DerivativesPharmacologyDrug-induced Liver InjuryDrug Discovery