A magneto-optical biochip for rapid assay based on the Cotton–Mouton effect of γ-Fe2O3@Au core/shell nanoparticles

Abstract

The assay process is simple and the whole testing time takes only 50 min including 3 min for the CM rotation measurement. The detection limit of our method for the spike glycoprotein S of SARS-CoV-2 is estimated as low as 0.27 ng/mL (3.4 pM).