Southern Medical Journal · 2021 · 10 citations · 11 references
MedicinePerioperative MedicineSurgeryAnesthesiaGeneral AnesthesiaPerioperative PharmacologyAnalgesiaNeuromuscular BlockadeNeuromuscular Blocking AgentsPostoperative MonitoringPostoperative NauseaPostoperative PainAbdominal Surgery RecoveryAbdominal Wall Hernia RepairAnalgesia For Abdominal SurgeryAnesthesia Reversal AgentsLaparoscopic CholecystectomyNeostigmine ReversalPostanesthesia Care Unit AssessmentSugammadex Reversal
OBJECTIVE: This study blindly evaluated sugammadex compared with neostigmine on length of stay in the postanesthesia care unit (PACU). METHODS: Fifty patients undergoing elective laparoscopic cholecystectomy or abdominal wall hernia repair consented to receive either sugammadex (2 mg/kg) or neostigmine (0.07 mg/kg) for the reversal of rocuronium neuromuscular blockade. Reversal agents were administered during surgical closing, and the train of four was measured until a twitch ratio of T4:T1 ≥ 0.9 was obtained to signify a robust reversal. Postreversal outcomes also were measured during PACU stay. Aldrete scores, pain visual analog scale score, and nausea were measured during the PACU stay. RESULTS: < 0.05). CONCLUSIONS: Sugammadex patients had a significantly shorter PACU stay.
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