miRNA-205-5p can be related to T2-polarity in Chronic Rhinosinusitis with Nasal Polyps

Abstract

miRNA 205-5p was increased in CRSwNP compared to controls, and it was especially expressed in CRSwNP patients with higher T2 inflammation (measured by both IL-5 levels and local eosinophilia) and worst clinical presentation. This miRNA may be an interesting target to be explored in patients with CRSwNP.