MICROSPONGES - A NOVEL DRUG DELIVERY SYSTEM

Abstract

Micro sponges are polymeric delivery systems composed of porous microspheres. They are tiny sponge-like spherical particles with a large porous surface. Moreover, they may enhance stability, reduce side effects and modify drug release favourably. Micro sponge technology has many favourable characteristics, which make it a versatile drug delivery vehicle. Micro sponge Systems are based on microscopic, polymer-based microspheres that can suspend or entrap a wide variety of substances, and can then be incorporated into a formulated product such as a gel, cream, liquid or powder. The outer surface is typically porous, allowing a sustained flow of substances out of the sphere. Micro sponges are porous, polymeric microspheres that are used mostly for topical use and have recently been used for oral administration. Micro sponges are designed to deliver a pharmaceutical active ingredient efficiently at the minimum dose and also to enhance stability, reduce side effects, and modify drug release.