Chemical Communications · 2021 · 18 citations · 18 references
EngineeringPeptide SciencePerfluorobiphenyl ComplexesPhosphorescence ImagingLuminescent RheniumPhotofunctional BioconjugatesSinglet Oxygenπ-Clamp SequenceBioimagingThermally Activated Delayed FluorescencePhotophysical PropertyMolecular ImagingBiochemistryPhotochemistryCysteine ResidueSupramolecular PhotochemistrySingle-molecule DetectionBiomolecular EngineeringNatural SciencesChemical ProbeSmall Molecules
We report herein new luminescent rhenium(I) perfluorobiphenyl complexes that reacted specifically with the cysteine residue of the π-clamp sequence (FCPF) to afford novel peptide-based imaging reagents, photosensitisers for singlet oxygen and enzyme sensors.
18
π-Clamp-mediated cysteine conjugation
Chi Zhang, Matthew Welborn, Tianyu Zhu et al. · Nature Chemistry · 2015 · 287 citations · Full text