Concepedia

X-ray characterization, Hirshfeld surface analysis, DFT calculations,<i>in vitro</i>and<i>in silico</i>lipoxygenase inhibition (LOX) studies of dichlorophenyl substituted 3-hydroxy-chromenones

Muhammad Naeem Ahmed, Mehreen Ghias, Syed Wadood Ali Shah, Muhammad Harris Shoaib, Muhammad Nawaz Tahir, Muhammad Ashfaq, Mahmoud A. A. Ibrahim, Hina Andleeb, Diego M. Gil, Antonio Frontera

New Journal of Chemistry · 2021 · 24 citations · 40 references

DOI

Concepts

Abstract

This work reports the synthesis, X-ray characterization and theoretical study of dichlorophenyl substituted 3-hydroxy-chromenones focusing on the low prevalence of halogen bonds and in vitro and in silico lipoxygenase inhibition (LOX) studies.

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