Copper-Catalyzed Cyclization of <i>N</i>-Propargyl Ynamides with Borane Adducts through B–H Bond Insertion

Abstract

-propargyl ynamides with borane adducts through B-H bond insertion has been developed. A series of valuable organoboron compounds are constructed in generally good yields with a wide substrate scope and good functional group tolerance under mild reaction conditions. Importantly, this protocol via vinyl cation intermediates constitutes a novel way of B-H bond insertion.