Archives of Endocrinology and Metabolism · 2021 · 10 citations · 28 references
MedicineNeurosciencePsychiatryEating DisordersNeuroendocrinologyNeuroplasticityAppetiteAppetite AssessmentAppetite RegulationDisordered EatingEating BehaviorsNutritional BiomarkersDisordered Eating AssessmentEating Behaviors AssessmentNeurotrophic Factor SignalingS100 Protein ExpressionSatiety MechanismsSatiety ResponseSerum BiomarkersSerum Nutrient Biomarkers
OBJECTIVE: To assess disordered eating, hunger and satiety perceptions in women with fibromyalgia (FM) compared to healthy controls (HC) and their association with biomarkers of brain plasticity (brain-derived neurotrophic factor (BDNF) and S100 calcium-binding protein B (S100B)). METHODS: Cross-sectional exploratory study. The sample included FM (n = 20) and HC (n = 19), matched to age and waist perimeter. Dysfunctional eating was assessed through the Three Factor Eating Questionnaire and Eating Disorders Examination with a questionnaire. Hunger and satiety levels were rated by a Numerical Scale. Serum leptin, S100B and BDNF were analyzed. RESULTS: = 0.004). CONCLUSION: The present findings support the hypothesis that the association between FM and obesity can be mediated by a hedonistic pathway. Further research is needed.
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