A Re-Innervated <i>in Vitro</i> Skin Model of Non-Histaminergic Itch and Skin Neurogenic Inflammation: PAR2-, TRPV1- and TRPA1-Agonist Induced Functionality - Concepedia

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A Re-Innervated <i>in Vitro</i> Skin Model of Non-Histaminergic Itch and Skin Neurogenic Inflammation: PAR2-, TRPV1- and TRPA1-Agonist Induced Functionality

DOI Full Paper Access

18

Citations

24

References

2021

Year

Nicolas Lebonvallet, Joachim W. Fluhr, C. Le Gall‐Ianotto, R. Leschiera, Matthieu Talagas, Alexia Reux, A. Bataille, Cécilia Brun, Thierry Oddos, Jean‐Pierre Pennec,

Skin Health and Disease

Abstract

The present model is suitable for studying itch and neurogenic inflammation pathways <i>in vitro</i>. We observed that activation of TRPV1, TRPA1 and PAR-2 leads to different response profiles in re-innervated skin explants.

References

	Year	Citations

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