Concepedia

Covalent and non-covalent coupling of a Au<sub>102</sub> nanocluster with a fluorophore: energy transfer, quenching and intracellular pH sensing

Eero Hulkko, Tanja Lahtinen, Varpu Marjomäki, Emmi Pohjolainen, Ville Saarnio, Karolina Sokołowska, Ardra Ajitha, Mikael Kuisma, Lauri Lehtovaara, Gerrit Groenhof,

Nanoscale Advances · 2021 · 14 citations · 35 references

DOIFull text

Open access

Concepts

Abstract

A covalently bound hybrid between an atomically precise gold nanocluster and a fluorescent dye is loaded into cells via endocytosis. Acidification of the endosomes activates fluorescence, enabling optical pH sensing inside live cells.

References

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