mBio · 2021 · 43 citations · 40 references
Veterinary MedicineImmunologyMicrobiologyHost-pathogen InteractionsInflammationInnate ImmunityHost-parasite Immune InteractionsInnate Immune Responses To ParasitesInnate Immunity To ParasitesNeutrophil BiologyParasitic InfectionsParasitic PathogenesisAcute Infection ImmunopathologyImmunopathology Of ToxoplasmosisNeutrophil Extracellular Trap FormationNeutrophil PhysiologyParasite-induced InflammationToxoplasmosis PathogenesisToxoplasmosis Pathology
Approximately one-third of the human population is estimated to be chronically infected with the obligate intracellular parasite Toxoplasma gondii . Humans are accidental hosts that are infected with T. gondii after consumption of undercooked meat or contaminated water.
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Neutrophil Extracellular Traps Kill Bacteria
Volker Brinkmann, Ulrike Reichard, Christian Goosmann et al. · Science · 2004 · 10.1K citations
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
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Novel cell death program leads to neutrophil extracellular traps
Tobias A. Fuchs, Ulrike Abu Abed, Christian Goosmann et al. · The Journal of Cell Biology · 2007 · 3.1K citations · Full text