International Journal of COPD · 2021 · 25 citations · 21 references
This study demonstrates that IOS has the potential to detect SAD in asymptomatic heavy smokers with preserved spirometry and with FEV3/FEV6 values in the normal range. We confirm that IOS provides parameters which can complement traditional measurements of pulmonary function.
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Small-Airway Obstruction and Emphysema in Chronic Obstructive Pulmonary Disease
John E. McDonough, Ren Yuan, Masaru Suzuki et al. · New England Journal of Medicine · 2011 · 1.2K citations · Full text