MALAT-1 is Associated with the Doxorubicin Resistance in U-2OS Osteosarcoma Cells

Abstract

Our study provides evidence that doxorubicin may upregulate MALAT-1 in osteosarcoma. Downregulating MALAT-1 in the doxorubicin resistance U-2OS cells could reverse the resistance and may improve chemotherapeutic efficiency. Some conclusions in previous literature may be one-sided.