Longitudinal preclinical evaluation of the novel radioligand [11C]CHDI-626 for PET imaging of mutant huntingtin aggregates in Huntington’s disease - Concepedia

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Longitudinal preclinical evaluation of the novel radioligand [11C]CHDI-626 for PET imaging of mutant huntingtin aggregates in Huntington’s disease

DOI Full Paper Access

25

Citations

29

References

2021

Year

Daniele Bertoglio, Jeroen Verhaeghe, Alan Miranda, Leonie Wyffels, Sigrid Stroobants, Ladislav Mrzljak, Vinod Khetarpal, Mette Skinbjerg, Longbin Liu, Celia Dominguez,

European Journal of Nuclear Medicine and Molecular Imaging

Abstract

With clinical evaluation underway, [<sup>11</sup>C]CHDI-626 PET imaging appears to be a suitable preclinical candidate marker to monitor natural HD progression and for the evaluation of mHTT-lowering therapies.

References

	Year	Citations

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