Concepedia

Publication | Open Access

Differential Effects of Estrogen Receptor Alpha and Beta on Endogenous Ligands of Peroxisome Proliferator-Activated Receptor Gamma in Papillary Thyroid Cancer

DOIFull Paper Access

18

Citations

35

References

2021

Year

Shucai Yang, Zhongqin Gong, Zhimin Liu, Minghui Wei, Lingbin Xue, Alexander C. Vlantis, Yang Zhang, Jason Y. K. Chan, C. Andrew van Hasselt, Xianhai Zeng,
Frontiers in Endocrinology

Abstract

The levels of endogenous PPARγ ligands PGJ2 and 15(S)-HETE are significantly decreased in PTC. The inhibition of ERα or activation of ERβ can inhibit PTC by stimulating the production of endogenous PPARγ ligands to induce apoptosis in cancer cells.

References

YearCitations

Page 1