Science Translational Medicine · 2021 · 98 citations · 38 references
Life SciencesImmunologyOncologyCancer ImmunologyImmunotherapyTumor ImmunologyAntitumor T Cell ResponsesCancer ImmunotherapyCheckpoint Inhibitor TherapyImmune Checkpoint InhibitorsImmune CheckpointsTumor-infiltrating LymphocytesImmune Checkpoint BiomarkersImmune Checkpoint Inhibitor BiomarkersImmune Checkpoint Inhibitor TherapyImmune Checkpoint Ligand ExpressionImmune Checkpoint ResistanceInhibitory Checkpoint Regulation
immunotype detects patients who are less likely to benefit from ICB and suggests a strategy for identifying actionable immune targets for further investigation.
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Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer
Naiyer A. Rizvi, Matthew D. Hellmann, Alexandra Snyder et al. · Science · 2015 · 7.9K citations
Medicine, Immunology, Oncology +17