Soluble tumor necrosis factor-alpha-induced hyperexcitability contributes to retinal ganglion cell apoptosis by enhancing Nav1.6 in experimental glaucoma - Concepedia

Concepedia

Publication | Open Access

Soluble tumor necrosis factor-alpha-induced hyperexcitability contributes to retinal ganglion cell apoptosis by enhancing Nav1.6 in experimental glaucoma

DOI Full Paper Access

45

Citations

69

References

2021

Year

Shuo Cheng, Hongning Wang, Lin‐Jie Xu, Fang Li, Yanying Miao, Bo Lei, Xinghuai Sun, Zhongfeng Wang

Journal of Neuroinflammation

Abstract

TNF-α/TNFR1 signaling induces RGC hyperexcitability by selectively upregulating Nav1.6 Na<sup>+</sup> channels, thus contributing to RGC apoptosis in glaucoma.

References

	Year	Citations

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