Oral <scp>RNAi</scp> toxicity assay suggests <i>clathrin heavy chain</i> as a promising molecular target for controlling the <scp>28</scp>‐spotted potato ladybird, <i>Henosepilachna vigintioctopunctata</i>

Abstract

We conclude that (i) species with numerous 21-nt matches in homologous genes are more likely to be susceptible to dsRNA; (ii) dsRNA can be safely designed to avoid negative effects on non-target organisms at both transcriptional and organismal levels; (iii) HvChc can be used as an efficient RNAi target gene to effectively manage H. vigintioctopunctata. © 2021 Society of Chemical Industry.