Superparamagnetic core–shell electrospun scaffolds with sustained release of IONPs facilitating <i>in vitro</i> and <i>in vivo</i> bone regeneration

Abstract

bone regeneration was observed after implanting PPT-Fe scaffolds in rat calvarial bone defects. Thus, we can conclude that the incorporation of IONPs into porous scaffolds for long-term release can provide a new strategy for BTE scaffold optimization and is a promising approach that can offer enhanced osteogenic capacity in clinical applications.