Investigation of the Role of Neurokinin‐1 Receptor Inhibition Using Aprepitant in the Apoptotic Cell Death through PI3K/Akt/NF‐<i>κ</i>B Signal Transduction Pathways in Colon Cancer Cells

Abstract

Towards this end, this study suggests that SP/NK1R system plays a vital role in the development of CRC, and pharmaceutical targeting of NK1R using aprepitant might be a promising treatment against CRC.