The effectiveness of surface disinfectants and a micellic H2O2 based water disinfectant on Candida auris

Abstract

ETH and QAC displayed in clinically recommended concentrations more than 5log₁₀ reduction and more than 80% XTT activity reduction for all of the Candida biofilms and planktonic cells. Only biofilms of C. auris NCPF8984 were additionally sensitive to all remaining disinfectants. All tested C. auris biofilms were sensitive to PP disinfectant and showed more than 5log₁₀ reduction. However, the XTT assay showed a reduction of less than 80% for the PP disinfectant, indicating the presence of active but non-culturable cells. The 25% mH₂O₂ (corresponding to 4.25% H₂O₂) killed Candida biofilms after 1 minute.