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Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood–brain barrier and knock down genes in the rodent CNS

Knockout MouseChromatinNeurodegenerative DiseasesMolecular NeuroscienceNeurogenomicsBlood–brain BarrierMedicineNatural SciencesNucleic Acid BiochemistryOligonucleotideMolecular BiologyCholesterol-functionalized Dna/rna HeteroduplexesMolecular NeurobiologyRodent CnsEpigenetic RegulationCell BiologyEpigeneticsNeurogenetics