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Publication | Open Access

Frequent LPA KIV-2 Variants Lower Lipoprotein(a) Concentrations and Protect Against Coronary Artery Disease

DOIFull Paper Access

85

Citations

24

References

2021

Year

Johanna F. Schachtl‐Riess, Azin Kheirkhah, Rebecca Grüneis, Silvia Di Maio, Sebastian Schoenherr, Gertraud Streiter, Jamie Lee Losso, Bernhard Paulweber, Kai‐Uwe Eckardt, Anna Köttgen,
Journal of the American College of Cardiology

Abstract

Functional variants in the previously inaccessible LPA KIV-2 region cooperate in determining Lp(a) variance and CAD risk. Even a moderate but lifelong genetic Lp(a) reduction translates to a noticeable CAD risk reduction.

References

YearCitations

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