YAP1-MAML2 Fusion as a Diagnostic Biomarker for Metaplastic Thymoma

Abstract

Our study explored the genetic alterations in epithelioid and spindle cell components in metaplastic thymoma. Furthermore, <i>YAP1-MAML2</i> gene rearrangements emerged as a potential diagnostic biomarker helpful for distinguishing metaplastic thymoma from type A and micronodular thymoma with lymphoid stroma.