Concepedia

Publication | Open Access

Tumor‐derived exosomal <i>BCYRN1</i> activates WNT5A/VEGF‐C/VEGFR3 feedforward loop to drive lymphatic metastasis of bladder cancer

DOIFull Paper Access

100

Citations

34

References

2021

Year

Hanhao Zheng, Changhao Chen, Yuming Luo, Min Yu, Wang He, Mingjie An, Bowen Gao, Yao Kong, Yiyao Ya, Yan Lin,
Clinical and Translational Medicine

Abstract

Our results uncover a novel mechanism by which exosomal BCYRN1 synergistically enhances VEGF-C/VEGFR3 signaling-induced lymphatic metastasis of BCa, indicating that BCYRN1 may serve as an encouraging therapeutic target for patients with BCa.

References

YearCitations

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