COVID-19 vaccine-associated acute cerebral venous thrombosis and pulmonary artery embolism

Abstract

The vaccination of ChAdOx1 nCoV-19 (AstraZeneca) may trigger the expression of antiplatelet antibodies, further resulting in thrombocytopenia and thrombotic events. We present a case of COVID-19 vaccine-associated immune thrombosis and thrombocytopenia. She experienced coexisting cerebral venous sinus thrombosis and pulmonary artery thromboembolism after receiving the first dose of ChAdOx1 nCoV-19 vaccine. The early diagnosis of these associated complications and optimal management can improve clinical outcomes.