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Publication | Open Access

Central role of c-Src in NOX5- mediated redox signalling in vascular smooth muscle cells in human hypertension

DOIFull Paper Access

43

Citations

33

References

2021

Year

Lívia L. Camargo, Augusto C. Montezano, Misbah Hussain, Yu Wang, Zhiguo Zou, Francisco J. Rios, Karla B Neves, Rhéure Alves-Lopes, Fazli Rabbi Awan, Tomasz J. Guzik,
Cardiovascular Research

Abstract

We define NOX5/ROS/c-Src as a novel feedforward signalling network in human VSMCs. Amplification of this system in hypertension contributes to VSMC dysfunction. Dampening the NOX5/ROS/c-Src pathway may ameliorate hypertension-associated vascular injury.

References

YearCitations

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