Concepedia

Publication | Closed Access

Fatty Acid Synthase–Suppressor Screening Identifies Sorting Nexin 8 as a Therapeutic Target for NAFLD

DOI

102

Citations

38

References

2021

Year

Yufeng Hu, Wenzhi He, Yongping Huang, Hui Xiang, Juan Guo, Yan Che, Xu Cheng, Fengjiao Hu, Manli Hu, Tengfei Ma,
Hepatology

Abstract

These data indicate that SNX8 is a key suppressor of NAFLD that promotes FASN proteasomal degradation. Targeting the SNX8-FASN axis is a promising strategy for NAFLD prevention and treatment.

References

YearCitations

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