Binary-Acid Catalysis with Sc(OTf)₃/TfOH in the Alkenylation of Arenes with Alkynes

Abstract

Herein we report binary acid Sc(OTf)₃/TfOH-catalyzed alkenylation of arenes with alkynes. In this system, the high-energy vinyl carbocations with activated and weakly coordinating trifluoromethanesulfonate anions by Lewis acid Sc(III) can undergo facile Friedel-Crafts reactions with arenes to give the desired adducts in up to 90% yield and with high <i>Z</i>-selectivity.