Gut · 2021 · 52 citations · 55 references
While any use of PPIs was not associated with an increased risk of colorectal cancer compared with H2RAs, prolonged use may be associated with a modest increased risk of this malignancy.
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Global patterns and trends in colorectal cancer incidence and mortality
Melina Arnold, Mónica S. Sierra, Mathieu Laversanne et al. · Gut · 2016 · 5.2K citations · Full text
Flexible regression models with cubic splines
Sylvain Durrleman, Richard Simon · Statistics in Medicine · 1989 · 2.6K citations