Cyclam-Modified Polyethyleneimine for Simultaneous TGFβ siRNA Delivery and CXCR4 Inhibition for the Treatment of CCl4-Induced Liver Fibrosis - Concepedia

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Cyclam-Modified Polyethyleneimine for Simultaneous TGFβ siRNA Delivery and CXCR4 Inhibition for the Treatment of CCl4-Induced Liver Fibrosis

DOI Full Paper Access

19

Citations

55

References

2021

Year

Aftab Ullah, Gang Chen, Abid Hussain, Hanif Khan, Azar Abbas, Zhanwei Zhou, Muhammad Shafiq, Saleem Ahmad, Usman Ali, Muhammad Usman,

International Journal of Nanomedicine

Abstract

Our findings validate the feasibility of using PEI-Cyclam as a siRNA delivery vector for simultaneous TGFβ siRNA delivery and CXCR4 inhibition for the combined anti-fibrotic effects in a setting of CCl<sub>4</sub>-induced liver fibrosis.

References

	Year	Citations

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