Concepedia

CD8 <sup>+</sup> T cells specific for conserved coronavirus epitopes correlate with milder disease in patients with COVID-19

Vamsee Mallajosyula, Conner Ganjavi, Saborni Chakraborty, Alana M. McSween, Ana Jimena Pavlovitch-Bedzyk, Julie Wilhelmy, Allison Nau, Monali Manohar, Kari C. Nadeau, Mark M. Davis

Science Immunology · 2021 · 171 citations · 57 references

DOIFull text

Open access

Concepts

Abstract

T cells with these conserved specificities are much more abundant in COVID-19 patients with mild disease versus those with a more severe illness, suggesting a protective role.

References

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