Combining Low Power Fractional CO₂ With QS‐NdYAG Toning in the Treatment of Melasma Reduces the Incidence of Punctate Leukoderma

Abstract

QS-Nd:YAG toning is significantly more effective than low power fractional CO₂ in the treatment of melasma when used separately. Although combining low power fractional CO₂ with QS-Nd:YAG toning does not increase its efficacy, it minimizes the incidence of the undesirable punctate leukoderma complication and achieves lower recurrence. This combination can thus be recommended as a safe and effective measure for the treatment of melasma. © 2021 Wiley Periodicals LLC.