Bleomycin induces fibrotic transformation of bone marrow stromal cells to treat height loss of intervertebral disc through the TGFβR1/Smad2/3 pathway - Concepedia

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Bleomycin induces fibrotic transformation of bone marrow stromal cells to treat height loss of intervertebral disc through the TGFβR1/Smad2/3 pathway

DOI Full Paper Access

28

Citations

32

References

2021

Year

Xiao Yang, Zhiqian Chen, Chen Chen, Han Chen, Yifan Zhou, Xunlin Li, Haijun Tian, Xiaofei Cheng, Kai Zhang, An Qin,

Stem Cell Research & Therapy

Abstract

Locally, injection of bleomycin in rats' IVD induced rapid fibrosis and maintained its height through the TGFβ-TGFβR1-SMAD2/3 signaling pathway.

References

	Year	Citations

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