Molecular docking studies of <i>Nigella sativa</i> L and <i>Curcuma xanthorrhiza Roxb</i> secondary metabolites against histamine <i>N</i> -methyltransferase with their ADMET prediction

Abstract

This study found several secondary metabolites of <i>N. sativa</i> L and <i>C. xanthorrhiza Roxb</i> which had activity as HNMT inhibitors. This research can likewise be utilized as a basis for further research, both <i>in vitro</i>, <i>in vivo</i>, and clinical trials related to the development of secondary metabolites from <i>N. sativa</i> L and <i>C. xanthorrhiza Roxb</i> as novel HNMT inhibitor compounds.