THE SELECTIVE USE OF ANTICOAGULANTS IN ACUTE MYOCARDIAL INFARCTION BASED ON INITIAL PROGNOSIS

Abstract

Article1 November 1954THE SELECTIVE USE OF ANTICOAGULANTS IN ACUTE MYOCARDIAL INFARCTION BASED ON INITIAL PROGNOSISMORTON M. HALPERN, M.D., LOUIS LEMBERG, M.D., MARTIN BELLE, M.D., HERBERT EICHERT, M.D., F.A.C.P.MORTON M. HALPERN, M.D., LOUIS LEMBERG, M.D., MARTIN BELLE, M.D., HERBERT EICHERT, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-41-5-942 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptReliable evidence accumulated in the last 10 years has indicated that anticoagulants are of decided value in the prevention and treatment of thromboembolic diseases. Beginning with Wright's report in 1945,1 the specific value of anticoagulants in the management of acute myocardial infarction has been adequately demonstrated by many investigators.The advisability of instituting anticoagulant therapy in every case of cardiac infarction has been challenged recently.2-5Inconvenience, expense, and certain known hazards inherent in anticoagulant therapy were stated to outweigh any benefits that might accrue from its use in the so-called "good risk" cases. One report6goes even further, by concluding...Bibliography1. Wright IS: Experiences with Dicumarol in the treatment of coronary thrombosis, Proc. Am. Federation Clin. Research 2: 28, 1945. Google Scholar2. RussekZohmanWhiteDoerner HIBLLGAA: Indications for bishydroxycoumarin (Dicumarol) in acute myocardial infarction, J. A. M. A. 145: 390, 1951. CrossrefMedlineGoogle Scholar3. Littmann D: The prevention of thrombo-embolism in acute coronary-artery disease, New England J. Med. 247: 205, 1952. CrossrefMedlineGoogle Scholar4. Schnur S: Mortality and other studies questioning evidence for and value of routine anticoagulant therapy in acute myocardial infarction, Circulation 7: 855, 1953. CrossrefMedlineGoogle Scholar5. FurmanGaleBillingsMeneely RHRGFTGR: Critical appraisal of anticoagulant therapy with Heparin and Dicumarol in coronary arteriosclerosis with myocardial infarction by comparison within prognostic categories, Am. J. Med. 7: 133, 1949. CrossrefGoogle Scholar6. FurmanBallGaleBillingsMeneely RHCORGFTGR: An evaluation of anticoagulant therapy in myocardial infarction based on prognostic categories, Am. J. Med. 14: 681, 1953. CrossrefMedlineGoogle Scholar7. Wright IS: An evaluation of anticoagulant therapy, Am. J. Med. 14: 720, 1953. CrossrefMedlineGoogle Scholar8. FeldmanO'ConnorFriedmanFischer LWRIAJW: Anticoagulant therapy in acute myocardial infarction, Am. Heart J. 44: 112, 1952. CrossrefMedlineGoogle Scholar9. RussekZohmanDoernerRussekWhite HIBLAAASLG: Age and survival in cases of acute myocardial infarction, J. A. M. A. 147: 1731, 1951. CrossrefMedlineGoogle Scholar10. LevineRosenbaum SAFF: Prognostic value of various clinical and electrocardiographic features of acute myocardial infarction. I. Immediate prognosis, Arch. Int. Med. 68: 913, 1941. CrossrefGoogle Scholar11. DoscherPoindexter NCA: Myocardial infarction without anticoagulant therapy: deaths, emboli and an analysis of factors influencing mortality, Am. J. Med. 8: 623, 1950. CrossrefMedlineGoogle Scholar12. BillingsKalstoneSpencerBallMeneely FTBMJLCOGR: Prognosis of acute myocardial infarction, Am. J. Med. 7: 356, 1949. CrossrefMedlineGoogle Scholar13. MasterJaffeeDack AMHLS: The treatment and immediate prognosis of coronary artery thrombosis, Am. Heart J. 12: 549, 1936. CrossrefGoogle Scholar14. NayBarnes RMAR: Incidence of embolic or thrombotic processes during immediate convalescence from acute myocardial infarction, Am. Heart J. 30: 65, 1945. CrossrefGoogle Scholar15. YaterTraumSpringBrownFitzgeraldGeislerWilcox WMHSWGRPMABP: Coronary artery disease in men 18-39 years of age, Am. Heart J. 36: 334, 1948. CrossrefMedlineGoogle Scholar16. Ernstene AC: Complications and sequelae of acute myocardial infarction, J. A. M. A. 150: 1069, 1952. CrossrefMedlineGoogle Scholar17. MasterDackJaffe AMSHL: Coronary thrombosis: an investigation of heart failure and other factors in the course and prognosis, Am. Heart J. 13: 330, 1937. CrossrefGoogle Scholar18. SmithKeyesDenham JFJWRM: Myocardial infarction: a study of the acute phase in 920 patients, Am. J. M. Sc. 221: 508, 1951. CrossrefMedlineGoogle Scholar19. Selzer A: The immediate sequelae of myocardial infarction: their relation to prognosis, Am. J. M. Sc. 216: 172, 1948. CrossrefMedlineGoogle Scholar20. YaterTraumBrownFitzgeraldGeislerWilcox WMAHWGRPMABB: Coronary artery disease in men eighteen to thirty-nine years of age, Am. Heart J. 36: 481, 1948. CrossrefMedlineGoogle Scholar21. WootenKyser RLFA: Mortality and treatment of myocardial infarction: a review of 455 cases, Ann. Int. Med. 38: 247, 1953. LinkGoogle Scholar22. BaerHeineKrasnoff SWFSW: The mortality of acute myocardial infarction in private practice, Am. J. M. Sc. 222: 500, 1951. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Miami, Florida*Received for publication January 4, 1954. Presented at the Regional Meeting of the American College of Physicians, St. Simons Island, Georgia, October 17, 1953.From the Departments of Cardiology, Jackson Memorial and Mercy Hospitals, Miami, Florida. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAn overview of anticoagulant therapy for coronary artery diseaseConservative Anticoagulant Therapy of Acute Myocardial InfarctionGEORGE C. GRIFFITH, M.D., F.A.C.P., DAVID LEAK, M.B., M.R.C.P. (EDIN.), BALAKRISHNA HEGDE, G.C.I.M., M.S. (MED.)Untersuchungen zur Pathophysiologie und Therapie des HerzinfarktesObservations on the immediate prognosis of acute myocardial infarctionDie Coronarerkrankungen. Coronarinsuffizienz, Angina pectoris und HerzinfarktAcute myocardial infarction in a city hospital∗Anticoagulant Therapy in Acute Myocardial InfarctionAnticoagulants in myocardial infarctionTHE SIGNIFICANCE OF HAEMORRHAGE DURING THE TREATMENT OF PATIENTS WITH THE COUMARIN ANTICOAGULANTSTHE PLACE OF ANTICOAGULANT THERAPY IN ACUTE MYOCARDIAL INFARCTIONLong-Term Anticoagulant Therapy of the Ambulatory Patient Following Myocardial InfarctionThe Prevention of Thromboembolic Complications in Myocardial Infarction by Anticoagulant TherapyThe present status of anticoagulantsSIMPLIFIED HEPARIN THERAPY OF IMPENDING AND ACUTE MYOCARDIAL INFARCTION*HYMAN ENGELBERG, M.D.An Evaluation of Anticoagulant Therapy in Acute Myocardial InfarctionPRESENT STATUS OF ANTICOAGULANT THERAPY IN THE TREATMENT OF MYOCARDIAL INFARCTION; THE USE AND MISUSE OF ANTICOAGULANTS; AN EVALUATION OF NEW ANTICOAGULANTS, THEIR INDICATIONS AND DOSAGE*IRVING S. WRIGHT, M.D., F.A.C.P.Anticoagulants for Myocardial InfarctionPulmonary Embolism 1 November 1954Volume 41, Issue 5Page: 942-951KeywordsAcute myocardial infarctionAnticoagulant therapyAnticoagulantsInfarction ePublished: 1 December 2008 Issue Published: 1 November 1954 PDF downloadLoading ...