Concepedia

Design, synthesis and biological evaluation of glycolamide, glycinamide, and β-amino carbonyl 1,2,4-triazole derivatives as DPP-4 inhibitors

Mao-Tsu Fuh, Ching‐Chun Tseng, Sin‐Min Li, Shuo‐En Tsai, Tsung-Jui Chuang, Chih‐Hao Lu, Ya–Chen Yang, Henry J. Tsai, Fung Fuh Wong

Bioorganic Chemistry · 2021 · 24 citations · 46 references

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References

46

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

Christopher K. Savile, Jacob M. Janey, Emily C. Mundorff et al. · Science · 2010 · 1.7K citations

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(2<i>R</i>)-4-Oxo-4-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-<i>a</i>]pyrazin- 7(8<i>H</i>)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine:  A Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

Dooseop Kim, Liping Wang, Maria Beconi et al. · Journal of Medicinal Chemistry · 2004 · 817 citations · Full text

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GEMDOCK: A generic evolutionary method for molecular docking

Jinn‐Moon Yang, Chun‐Chen Chen · Proteins Structure Function and Bioinformatics · 2004 · 699 citations

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Dipeptidyl Peptidase IV Inhibition for the Treatment of Type 2 Diabetes

George R. Lankas, Barbara Leiting, Ranabir Sinha Roy et al. · Diabetes · 2005 · 491 citations · Full text

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Highly Efficient Asymmetric Synthesis of Sitagliptin

Karl B. Hansen, Yi Hsiao, Feng Xu et al. · Journal of the American Chemical Society · 2009 · 308 citations

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