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Feature engineering and machine learning for causality assessment in pharmacovigilance: Lessons learned from application to the FDA Adverse Event Reporting System

Systems PharmacologyEpidemiologyHealth InformaticsMachine LearningHealth PolicyPredictive ToxicologyFeature EngineeringPredictive AnalyticsAdverse Outcome PathwayTime-varying ConfoundingPharmacovigilanceCausality AssessmentPublic HealthMedicineCausal InferenceAdverse Drug ReactionCausal Model