Enantioselective organocatalytic sequential Michael-cyclization of functionalized nitroalkanes to 2-hydroxycinnamaldehydes: synthesis of benzofused dioxa[3.3.1] and oxa[4.3.1] methylene-bridged compounds

Abstract

An organocatalytic enantioselective conjugate addition-initiated reaction sequence of 2-hydroxycinnamaldehydes with various functionalized nitroalkanes has been described to synthesize structurally diverse chromane-containing compounds.