Cooperative Asymmetric Catalysis with Dendrimeric [Co(salen)] Complexes

Abstract

Dendrimeric catalysts can present catalytic units in close proximity, thereby inducing useful cooperative effects (see picture). Commercial dendrimers were derivatized with chiral [Co(salen)] complexes and found to display enhanced reactivity relative to monomeric or even dimeric analogues in the hydrolytic kinetic resolution of epoxides.