Cone beam CT based validation of neural network generated synthetic CTs for radiotherapy in the head region

Abstract

The dosimetric results demonstrate good agreement between sCT, CBCT, and pCT based calculations. A properly applied CBCT conversion method can serve as a tool for quality assurance procedures in an MR only radiotherapy workflow for head patients. Dosimetric deviations of DVH metrics between sCT and CBCTs of larger than 2% should be followed up. A systematic shift of approximately 1% should be taken into account when using the <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>C</mml:mi> <mml:mi>B</mml:mi> <mml:mi>C</mml:mi> <mml:msub><mml:mi>T</mml:mi> <mml:mi>RS</mml:mi></mml:msub> </mml:mrow> </mml:math> approach in an MR only workflow.