Inhaled bacteriophage therapy in a porcine model of pneumonia caused by <scp><i>Pseudomonas aeruginosa</i></scp> during mechanical ventilation

Abstract

Our findings demonstrated (i) the feasibility of delivering large amounts of active phages by nebulization during mechanical ventilation and (ii) rapid control of in situ infection by inhaled bacteriophage in an experimental model of P. aeruginosa pneumonia with high translational value.