Proflavine and zinc chloride “team chemistry”: combining antibacterial agents <i>via</i> solid-state interaction

Abstract

Mechanochemical and solution reaction of ZnCl₂ with proflavine yields the antimicrobials [HPF]₂[ZnCl₄]·H₂O and ZnCl₃(HPF), more active, with respect to the separate components and the AgNO₃ standard, towards <italic>P. aeruginosa</italic>, <italic>E. coli</italic> and <italic>S. aureus</italic>.