Fecal Enterotoxigenic Bacteroides fragilis–Peptostreptococcus stomatis–Parvimonas micra Biomarker for Noninvasive Diagnosis and Prognosis of Colorectal Laterally Spreading Tumor

Abstract

Fecal microbiome signature (<i>ETBF</i>-<i>P. stomatis</i>-<i>P. micra</i>) can diagnose LSTs with high accuracy. <i>ETBF</i>, <i>P. stomatis</i>, and <i>P. micra</i> were related to malignant LST and <i>P. stomatis</i> exhibited high predictive value on the adenoma recurrence after resection of LSTs. The fecal microbiome signature of LST may provide a noninvasive alternative to early detect LST and predict the adenoma recurrence risk after resections of LSTs.