CATMoS: Collaborative Acute Toxicity Modeling Suite

Abstract

CATMoS is being evaluated by regulatory agencies for its utility and applicability as a potential replacement for <i>in vivo</i> rat acute oral toxicity studies. CATMoS predictions for more than 800,000 chemicals have been made available via the National Toxicology Program's Integrated Chemical Environment tools and data sets (ice.ntp.niehs.nih.gov). The models are also implemented in a free, standalone, open-source tool, OPERA, which allows predictions of new and untested chemicals to be made. https://doi.org/10.1289/EHP8495.