Concepedia

Publication | Open Access

ERK/Drp1‐dependent mitochondrial fission contributes to HMGB1‐induced autophagy in pulmonary arterial hypertension

DOIFull Paper Access

125

Citations

51

References

2021

Year

Wei Feng, Jian Wang, Xin Yan, Qianqian Zhang, Limin Chai, Qingting Wang, Wenhua Shi, Yuqian Chen, Jin Liu, Zhan Qu,
Cell Proliferation

Abstract

HMGB1 promotes PASMCs proliferation/migration and pulmonary vascular remodelling by activating ERK1/2/Drp1/Autophagy/BMPR2/Id1 axis, suggesting that this cascade might be a potential novel target for management of PAH.

References

YearCitations

Page 1